The most remarkable features of the Krka river valley are its scenic beauty and a large number of ancient castles and monasteries.

An island in the middle of the river is occupied by Kostanjevica na Krki, a medieval little town first mentioned in 1091. Just a short distance away, on a river bank, stands a Cistercian monastery founded by Bernard Spanheim in 1234, one of Slovenia's most important architectural monuments. The monastery, renowned as one of the Duchy of Carniola's wealthiest estates, was dissolved by the Austrian emperor Josef II in 1758. The building now houses a permanent collection of works by the renowned Slovenian 20th century painter Božidar Jakac.

Otočec Castle, also situated in the scenic surroundings of a Krka river island, combines Renaissance and Baroque features. It houses a hotel and a restaurant. Close by, you can find Struga Castle, a fine example of Gothic and Renaissance architecture, which houses an equestrian centre.

About 20 kilometres to the south-east, sheltered in a valley at the foot of the Gorjanci mountain range, stands the Carthusian monastery of Pleterje. It was built between 1403 and 1413 on commission from Hermann II of Celje. From 1595 to 1772 it was owned by the Jesuits. In 1899 it was repurchased by the Carthusian Order, an originally French order of monks, who still manage it. The monastery is not open to the public, but it is possible to view its beautiful Gothic chapel, get acquainted with its history, and purchase famous herbal teas, honey-bee products, wines and spirits prepared by monks using unique recipes.

At the end of the valley, near the renowned thermal spa resort of Čatež, where the Krka river flows into the Sava, stands Mokrice Castle, surrounded by a magnificent park covering 60 hectares of land. The castle, first mentioned in 1444, was rebuilt in the Renaissance style. Today it houses a five-star hotel boasting its own golf course and riding school.